DuPont Nutrition & Health Microbiome Venture announces third strategic academic partnership
The new collaboration with INRA Micalis-MGP will concentrate on DuPont’s probiotic strains and the understanding of their mechanism of action on human health.
Copenhagen, Denmark-based DuPont Nutrition & Health Microbiome Venture announced its third strategic research and development partnership. The newly forged relationship with INRA (French National Institute for Agricultural Research), through both the Micalis Institute and MetaGenoPolis, a pre-industrial demonstrator, will be focused on deciphering the molecular mechanisms of action of DuPont’s probiotic strains through a functional metagenomics approach.
INRA has developed and validated a high-throughput screening platform to test the effect of large DNA fragments in genomic or metagenomic libraries on intestinal epithelial cell lines modified with reporter gene technology, DuPont said. This allows the screening of genomic and metagenomic clones on various reporter systems targeting pathways involved in homeostasis, metabolism and immune control, as well as enteroendocrine cell activation.